Molecular Design of Antifouling Polymer Brushes Using Sequence-Specific Peptoids.

ABSTRACT: Material systems that can be used to flexibly and precisely define the chemical nature and molecular arrangement of a surface would be invaluable for the control of complex biointerfacial interactions. For example, progress in antifouling polymer biointerfaces that prevent non-specific protein adsorption and cell attachment, which can significantly improve the performance of an array of biomedical and industrial applications, is hampered by a lack of chemical models to identify the molecular features conferring their properties. Poly(N-substituted glycine) "peptoids" are peptidomimetic polymers that can be conveniently synthesized with specific monomer sequences and chain lengths, and are presented as a versatile platform for investigating the molecular design of antifouling polymer brushe

SUBMITTER: Lau KH 

PROVIDER: S-EPMC4497591 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature