Drosophila anti-nematode and antibacterial immune regulators revealed by RNA-Seq.

ABSTRACT:

Background

Drosophila melanogaster activates a variety of immune responses against microbial infections. However, information on the Drosophila immune response to entomopathogenic nematode infections is currently limited. The nematode Heterorhabditis bacteriophora is an insect parasite that forms a mutualistic relationship with the gram-negative bacteria Photorhabdus luminescens. Following infection, the nematodes release the bacteria that quickly multiply within the insect and produce several toxins that eventually kill the host. Although we currently know that the insect immune system interacts with Photorhabdus, information on interaction with the nematode vector is scarce.

Results

Here we have used next generation RNA-sequencing to analyze the transcriptional profile of

SUBMITTER: Castillo JC 

PROVIDER: S-EPMC4499211 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature