Magnetic Resonance Imaging of Human Tissue-Engineered Adipose Substitutes.

ABSTRACT: Adipose tissue (AT) substitutes are being developed to answer the strong demand in reconstructive surgery. To facilitate the validation of their functional performance in vivo, and to avoid resorting to excessive number of animals, it is crucial at this stage to develop biomedical imaging methodologies, enabling the follow-up of reconstructed AT substitutes. Until now, biomedical imaging of AT substitutes has scarcely been reported in the literature. Therefore, the optimal parameters enabling good resolution, appropriate contrast, and graft delineation, as well as blood perfusion validation, must be studied and reported. In this study, human adipose substitutes produced from adipose-derived stem/stromal cells using the self-assembly approach of tissue engineering were implanted into athymi

SUBMITTER: Proulx M 

PROVIDER: S-EPMC4499784 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature