BDNF Val(66)Met and 5-HTTLPR Genotype are Each Associated with Visual Scanning Patterns of Faces in Young Children.

ABSTRACT: Previous studies have documented both neuroplasticity-related BDNF Val(66)Met and emotion regulation-related 5-HTTLPR polymorphisms as genetic variants that contribute to the processing of emotions from faces. More specifically, research has shown the BDNF Met allele and the 5-HTTLPR Short allele to be associated with mechanisms of negative affectivity that relate to susceptibility for psychopathology. We examined visual scanning pathways in response to angry, happy, and neutral faces in relation to BDNF Val(66)Met and 5-HTTLPR genotyping in 49 children aged 4-7 years. Analyses revealed that variations in the visual processing of facial expressions of anger interacted with BDNF Val(66)Met genotype, such that children who carried at least one low neuroplasticity Met allele exhibited a vigil

SUBMITTER: Christou AI 

PROVIDER: S-EPMC4500100 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature