Mapping the zoonotic niche of Lassa fever in Africa.

ABSTRACT:

Background

Lassa fever is a viral haemorrhagic illness responsible for disease outbreaks across West Africa. It is a zoonosis, with the primary reservoir species identified as the Natal multimammate mouse, Mastomys natalensis. The host is distributed across sub-Saharan Africa while the virus' range appears to be restricted to West Africa. The majority of infections result from interactions between the animal reservoir and human populations, although secondary transmission between humans can occur, particularly in hospital settings.

Methods

Using a species distribution model, the locations of confirmed human and animal infections with Lassa virus (LASV) were used to generate a probabilistic surface of zoonotic transmission potential across sub-Saharan Africa.

Results

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SUBMITTER: Mylne AQ 

PROVIDER: S-EPMC4501400 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature