The global distribution of Crimean-Congo hemorrhagic fever.

ABSTRACT:

Background

Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne infection caused by a virus (CCHFV) from the Bunyaviridae family. Domestic and wild vertebrates are asymptomatic reservoirs for the virus, putting animal handlers, slaughter-house workers and agricultural labourers at highest risk in endemic areas, with secondary transmission possible through contact with infected blood and other bodily fluids. Human infection is characterized by severe symptoms that often result in death. While it is known that CCHFV transmission is limited to Africa, Asia and Europe, definitive global extents and risk patterns within these limits have not been well described.

Methods

We used an exhaustive database of human CCHF occurrence records and a niche modeling framework to map the glo

SUBMITTER: Messina JP 

PROVIDER: S-EPMC4501401 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature