5-Arylvinyl-2,2'-bipyridyls: Bright "push-pull" dyes as components in fluorescent indicators for zinc ions.

ABSTRACT: This article reviews the zinc(II)-dependent photophysical properties of arylvinylbipyridines (AVBs), a class of fluoroionophores in which 2,2'-bipyridyl and an aryl moiety are electronically conjugated. Zinc(II) binding of an AVB may lead to an emission bathochromic shift of the fluoroionophore without diminishing its fluorescence quantum yield. This observation can be explained using the excited state model of electron donor-π bridge-electron acceptor "push-pull" fluorophores, in which the bipy moiety acts as an electron acceptor, and zinc(II)-coordination strengthens its electron affinity. The spectral sensitivity of bipy-containing fluoroionophores, such as AVBs, to zinc(II) can be exploited to prepare fluorescent indicators for this ion. In several cases, AVB moieties are incorporated

SUBMITTER: Zhu L 

PROVIDER: S-EPMC4502440 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature