In vivo classification of colorectal neoplasia using high-resolution microendoscopy: Improvement with experience.

ABSTRACT:

Background and aims

High-resolution microendoscopy (HRME) is a novel, low-cost "optical biopsy" technology that allows for subcellular imaging. The study aim was to evaluate the learning curve of HRME for the differentiation of neoplastic from non-neoplastic colorectal polyps.

Methods

In a prospective cohort fashion, a total of 162 polyps from 97 patients at a single tertiary care center were imaged by HRME and classified in real time as neoplastic (adenomatous, cancer) or non-neoplastic (normal, hyperplastic, inflammatory). Histopathology was the gold standard for comparison. Diagnostic accuracy was examined at three intervals over time throughout the study; the initial interval included the first 40 polyps, the middle interval included the next 40 polyps examined, and the

SUBMITTER: Parikh ND 

PROVIDER: S-EPMC4504008 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature