Epigenome data release: a participant-centered approach to privacy protection.

ABSTRACT: Large-scale epigenome mapping by the NIH Roadmap Epigenomics Project, the ENCODE Consortium and the International Human Epigenome Consortium (IHEC) produces genome-wide DNA methylation data at one base-pair resolution. We examine how such data can be made open-access while balancing appropriate interpretation and genomic privacy. We propose guidelines for data release that both reduce ambiguity in the interpretation of open-access data and limit immediate access to genetic variation data that are made available through controlled access.

SUBMITTER: Dyke SO 

PROVIDER: S-EPMC4504083 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature