The human burst suppression electroencephalogram of deep hypothermia.

ABSTRACT:

Objective

Deep hypothermia induces 'burst suppression' (BS), an electroencephalogram pattern with low-voltage 'suppressions' alternating with high-voltage 'bursts'. Current understanding of BS comes mainly from anesthesia studies, while hypothermia-induced BS has received little study. We set out to investigate the electroencephalogram changes induced by cooling the human brain through increasing depths of BS through isoelectricity.

Methods

We recorded scalp electroencephalograms from eleven patients undergoing deep hypothermia during cardiac surgery with complete circulatory arrest, and analyzed these using methods of spectral analysis.

Results

Within patients, the depth of BS systematically depends on the depth of hypothermia, though responses vary between patients

SUBMITTER: Westover MB 

PROVIDER: S-EPMC4504839 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature