PLA2-responsive and SPIO-loaded phospholipid micelles.

ABSTRACT: PLA2-responsive and superparamagnetic iron oxide (SPIO) nanoparticle-loaded phospholipid micelles were developed. The release of a phospholipid-conjugated dye from these micelles was triggered due to phospholipid degradation by phospholipase A2. The high relaxivity of the encapsulated SPIO could enable non-invasive magnetic resonance imaging.

SUBMITTER: Gao Q 

PROVIDER: S-EPMC4506235 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature