Synergistic inhibition of Haemonchus contortus exsheathment by flavonoid monomers and condensed tannins.

ABSTRACT: This study investigated the separate and combined anthelmintic (AH) effects of different phenolic compounds, including condensed tannins and flavonoids, all of which are known to occur in willow leaves, a potentially valuable dry season feed. A range of contrasting model tannins, which span the whole range of willow tannins, were isolated from tilia flowers, goat willow leaves, black currant leaves and red currant leaves. All together, the tested compounds represented the major tannin types (procyanidins and prodelphinidins) and flavonoid types (flavonols, flavones and flavanones). The larval exsheathment inhibition assay (LEIA) was used to assess their in vitro effects on Haemonchus contortus third stage larvae. Arbutin, vanillic acid, and taxifolin proved to be ineffective whereas naring

SUBMITTER: Klongsiriwet C 

PROVIDER: S-EPMC4506970 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature