Late varicella-zoster virus dendriform keratitis in patients with histories of herpes zoster ophthalmicus.

ABSTRACT:

Purpose

To describe the characteristics and course of late varicella-zoster virus (VZV) dendriform keratitis in patients with histories of herpes zoster ophthalmicus (HZO); to describe responses of corneal lesions to antiviral treatment; and to investigate risk factors for recurrence.

Design

Retrospective case series.

Methods

Included were patients known to have 1 or more episodes of dendriform lesions beginning at least 2 weeks after HZO in 2 academic practices. Epithelial lesions were evaluated for the presence of VZV DNA by a polymerase chain reaction assay. Demographic, medical, and ophthalmic data were collected for each episode. Responses to treatment with antiviral medications were evaluated. Cumulative risk of recurrence was determined using Kaplan-Meier analy

SUBMITTER: Hu AY 

PROVIDER: S-EPMC4507370 | biostudies-literature | 2010 Feb

REPOSITORIES: biostudies-literature