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Oleanolic acid and ursolic acid inhibit peptidoglycan biosynthesis in Streptococcus mutans UA159.

ABSTRACT: In this study, we revealed that OA and UA significantly inhibited the expression of most genes related to peptidoglycan biosynthesis in S. mutans UA159. To the best of our knowledge, this is the first report to introduce the antimicrobial mechanism of OA and UA against S. mutans.

SUBMITTER: Park SN 

PROVIDER: S-EPMC4507558 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature

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Oleanolic acid and ursolic acid inhibit peptidoglycan biosynthesis in Streptococcus mutans UA159.

Park Soon-Nang SN   Ahn Sug-Joon SJ   Kook Joong-Ki JK  

Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] 20150601 2

In this study, we revealed that OA and UA significantly inhibited the expression of most genes related to peptidoglycan biosynthesis in S. mutans UA159. To the best of our knowledge, this is the first report to introduce the antimicrobial mechanism of OA and UA against S. mutans. ...[more]

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