Identification of regulatory network hubs that control lipid metabolism in Chlamydomonas reinhardtii.

ABSTRACT: Microalgae-based biofuels are promising sources of alternative energy, but improvements throughout the production process are required to establish them as economically feasible. One of the most influential improvements would be a significant increase in lipid yields, which could be achieved by altering the regulation of lipid biosynthesis and accumulation. Chlamydomonas reinhardtii accumulates oil (triacylglycerols, TAG) in response to nitrogen (N) deprivation. Although a few important regulatory genes have been identified that are involved in controlling this process, a global understanding of the larger regulatory network has not been developed. In order to uncover this network in this species, a combined omics (transcriptomic, proteomic and metabolomic) analysis was applied to cells gr

SUBMITTER: Gargouri M 

PROVIDER: S-EPMC4507760 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature