Accuracy of Presepsin in Sepsis Diagnosis: A Systematic Review and Meta-Analysis.

ABSTRACT:

Objective

It's difficult to differentiate sepsis from non-sepsis, especially non-infectious SIRS, because no good standard exists for proof of infection. Soluble CD14 subtype (sCD14-ST), recently re-named presepsin, was identified as a new marker for the diagnosis of sepsis in several reports. However, the findings were based on the results of individual clinical trials, rather than a comprehensive and overall estimation. Thus, we conducted this systematic review and meta-analysis to estimate the pooled accuracy of presepsin in patients with sepsis suspect.

Methods

A comprehensive electronic search was performed via internet retrieval system up to 15 December 2014. Methodological quality assessment was applied by using the QUADAS2 tool. The diagnostic value of presepsin in s

SUBMITTER: Wu J 

PROVIDER: S-EPMC4507991 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature