An integrated methodology for the assessment of environmental health implications during thermal decomposition of nano-enabled products.

ABSTRACT: The proliferation of nano-enabled products (NEPs) renders human exposure to engineered nanomaterials (ENMs) inevitable. Over the last decade, the risk assessment paradigm for nanomaterials focused primarily on potential adverse effect of pristine, as-prepared ENMs. However, the physicochemical properties of ENMs may be drastically altered across their life-cycle (LC), especially when they are embedded in various NEP matrices. Of a particular interest is the end-of-life scenario by thermal decomposition. The main objective of the current study is to develop a standardized, versatile and reproducible methodology that allows for the systematic physicochemical and toxicological characterization of the NEP thermal decomposition. The developed methodology was tested for an industry-relevant NEP

SUBMITTER: Sotiriou GA 

PROVIDER: S-EPMC4508024 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature