Microribonucleic acid dysregulations in children and adolescents with obsessive-compulsive disorder.

ABSTRACT:

Aim

Obsessive-compulsive disorder (OCD) is a disorder characterized by the presence of obsessions and/or compulsions. Although disorder etiology and pathogenesis remains unknown, several theories about OCD development have been proposed, and many researchers believe that it is caused by both genetic and environmental factors. In the current study, our aim was to investigate miRNA levels in OCD.

Methods

In the current study, we evaluated miR18a-5p, miR22-3p, miR24-3p, miR106b-5p, miR107, miR125b-5p, and miR155a-5p levels in child and adolescent OCD patients. The research sample consisted of a group of 23 OCD patients and 40 healthy volunteer controls.

Results

There was no significant difference in age and sex between the two groups (P>0.05). The levels of miR22-3p, miR

SUBMITTER: Kandemir H 

PROVIDER: S-EPMC4508068 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature