On the importance of sensor height variation for detection of magnetic labels by magnetoresistive sensors.

ABSTRACT: Magnetoresistive sensors are widely used for biosensing by detecting the signal from magnetic labels bound to a functionalized area that usually covers the entire sensor structure. Magnetic labels magnetized by a homogeneous applied magnetic field weaken and strengthen the applied field when they are over and outside the sensor area, respectively, and the detailed origin of the sensor signal in experimental studies has not been clarified. We systematically analyze the signal from both a single sensor stripe and an array of sensor stripes as function of the geometrical parameters of the sensor stripes as well as the distribution of magnetic labels over the stripes. We show that the signal from sensor stripes with a uniform protective coating, contrary to conventional wisdom in the field, is

SUBMITTER: Henriksen AD 

PROVIDER: S-EPMC4508666 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature