Dataset Information
Association of CYP2J2 gene polymorphisms with ischemic stroke.
Ontology highlight
ABSTRACT: Objective
The present study aims to investigate the relationship between CYP2J2 gene polymorphisms and ischemic stroke (IS) in a Chinese Han population.Methods
We performed a case-control study including 300 stroke patients and 300 healthy control subjects to compare the distribution of genetic polymorphism G-50T in CYP2J2 gene.Results
We found GT genotype of G-50T in CYP2J2 gene was associated with the risk for IS (13.7% vs. 7.7%, P = 0.037). After adjustment of confounders, the difference remains significant (OR = 1.890, 95% CI: 1.042-3.011).Conclusion
CYP2J2 gene polymorphism might increase the risk of stroke in Chinese population.
SUBMITTER: Li Q
PROVIDER: S-EPMC4509331 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Publications
Association of CYP2J2 gene polymorphisms with ischemic stroke.
International journal of clinical and experimental medicine 20150515 5
<h4>Objective</h4>The present study aims to investigate the relationship between CYP2J2 gene polymorphisms and ischemic stroke (IS) in a Chinese Han population.<h4>Methods</h4>We performed a case-control study including 300 stroke patients and 300 healthy control subjects to compare the distribution of genetic polymorphism G-50T in CYP2J2 gene.<h4>Results</h4>We found GT genotype of G-50T in CYP2J2 gene was associated with the risk for IS (13.7% vs. 7.7%, P = 0.037). After adjustment of confound ...[more]