Outcomes of Infants Starting Antiretroviral Therapy in Southern Africa, 2004-2012.

ABSTRACT:

Background

There are limited published data on the outcomes of infants starting antiretroviral therapy (ART) in routine care in Southern Africa. This study aimed to examine the baseline characteristics and outcomes of infants initiating ART.

Methods

We analyzed prospectively collected cohort data from routine ART initiation in infants from 11 cohorts contributing to the International Epidemiologic Database to Evaluate AIDS in Southern Africa. We included ART-naive HIV-infected infants aged <12 months initiating ≥3 antiretroviral drugs between 2004 and 2012. Kaplan-Meier estimates were calculated for mortality, loss to follow-up (LTFU), transfer out, and virological suppression. We used Cox proportional hazard models stratified by cohort to determine baseline characteristics

SUBMITTER: Porter M 

PROVIDER: S-EPMC4509628 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature