Application of programmable bio-nano-chip system for the quantitative detection of drugs of abuse in oral fluids.

ABSTRACT:

Objective

There is currently a gap in on-site drug of abuse monitoring. Current detection methods involve invasive sampling of blood and urine specimens, or collection of oral fluid, followed by qualitative screening tests using immunochromatographic cartridges. While remote laboratories then may provide confirmation and quantitative assessment of a presumptive positive, this instrumentation is expensive and decoupled from the initial sampling making the current drug-screening program inefficient and costly. The authors applied a noninvasive oral fluid sampling approach integrated with the in-development chip-based Programmable bio-nano-chip (p-BNC) platform for the detection of drugs of abuse.

Method

The p-BNC assay methodology was applied for the detection of tetrahydrocan

SUBMITTER: Christodoulides N 

PROVIDER: S-EPMC4509839 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature