Relationship of pericardial fat with lipoprotein distribution: The Multi-Ethnic study of atherosclerosis.

ABSTRACT:

Objective

Pericardial fat and lipoprotein abnormalities contribute to increased risk of cardiovascular disease (CVD). We investigated the relationship between pericardial fat volume and lipoprotein distribution, and whether the association of pericardial fat volume with subclinical atherosclerosis and incident CVD events differs according to lipoprotein distribution.

Methods

We analyzed data from 5407 participants from the Multi-Ethnic Study of Atherosclerosis who had measurements of pericardial fat volume, lipoprotein distribution, carotid intima-media thickness (IMT), and coronary artery calcium (CAC). All participants were free of clinically apparent CVD at baseline. Incident CVD was defined as any adjudicated CVD event.

Results

After adjusting for demographic fact

SUBMITTER: Ong KL 

PROVIDER: S-EPMC4510019 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature