Quantitative analysis of the myelin g-ratio from electron microscopy images of the macaque corpus callosum.

ABSTRACT: We provide a detailed morphometric analysis of eight transmission electron micrographs (TEMs) obtained from the corpus callosum of one cynomolgus macaque. The raw TEM images are included in the article, along with the distributions of the axon caliber and the myelin g-ratio in each image. The distributions are analyzed to determine the relationship between axon caliber and g-ratio, and compared against the aggregate metrics (myelin volume fraction, fiber volume fraction, and the aggregate g-ratio), as defined in the accompanying research article entitled 'In vivo histology of the myelin g-ratio with magnetic resonance imaging' (Stikov et al., NeuroImage, 2015).

SUBMITTER: Stikov N 

PROVIDER: S-EPMC4510539 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature