Birth weight and later life adherence to unhealthy lifestyles in predicting type 2 diabetes: prospective cohort study.

ABSTRACT:

Objectives

To prospectively assess the joint association of birth weight and established lifestyle risk factors in adulthood with incident type 2 diabetes and to quantitatively decompose the attributing effects to birth weight only, to adulthood lifestyle only, and to their interaction.

Design

Prospective cohort study.

Setting

Health Professionals Follow-up Study (1986-2010), Nurses' Health Study (1980-2010), and Nurses' Health Study II (1991-2011).

Participants

149,794 men and women without diabetes, cardiovascular disease, or cancer at baseline.

Main outcome measure

Incident cases of type 2 diabetes, identified through self report and validated by a supplementary questionnaire. Unhealthy lifestyle was defined on the basis of body mass index, smoking, p

SUBMITTER: Li Y 

PROVIDER: S-EPMC4510778 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature