Association between the level of circulating adiponectin and prediabetes: A meta-analysis.

ABSTRACT:

Aims/introduction

Adiponectin has been proposed to have an essential role in the regulation of insulin sensitivity and metabolism, but previous studies on levels of adiponectin in prediabetes remain inconsistent. The present study aimed to assess the differences of adiponectin levels between prediabetes patients and healthy controls by carrying out a meta-analysis.

Materials and methods

We carried out a systematic literature search of PubMed, EMBASE, and other databases for case-control studies and cohort studies measuring adiponectin levels in serum or plasma from prediabetes patients and healthy controls. The pooled weighted mean difference (WMD) and 95% confidence interval (CI) were used to estimate the association between adiponectin levels and prediabetes.

Results

SUBMITTER: Lai H 

PROVIDER: S-EPMC4511301 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature