Relationships between protein-encoding gene abundance and corresponding process are commonly assumed yet rarely observed.

ABSTRACT: For any enzyme-catalyzed reaction to occur, the corresponding protein-encoding genes and transcripts are necessary prerequisites. Thus, a positive relationship between the abundance of gene or transcripts and corresponding process rates is often assumed. To test this assumption, we conducted a meta-analysis of the relationships between gene and/or transcript abundances and corresponding process rates. We identified 415 studies that quantified the abundance of genes or transcripts for enzymes involved in carbon or nitrogen cycling. However, in only 59 of these manuscripts did the authors report both gene or transcript abundance and rates of the appropriate process. We found that within studies there was a significant but weak positive relationship between gene abundance and the correspondin

SUBMITTER: Rocca JD 

PROVIDER: S-EPMC4511926 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature