Microbial dark matter ecogenomics reveals complex synergistic networks in a methanogenic bioreactor.

ABSTRACT: Ecogenomic investigation of a methanogenic bioreactor degrading terephthalate (TA) allowed elucidation of complex synergistic networks of uncultivated microorganisms, including those from candidate phyla with no cultivated representatives. Our previous metagenomic investigation proposed that Pelotomaculum and methanogens may interact with uncultivated organisms to degrade TA; however, many members of the community remained unaddressed because of past technological limitations. In further pursuit, this study employed state-of-the-art omics tools to generate draft genomes and transcriptomes for uncultivated organisms spanning 15 phyla and reports the first genomic insight into candidate phyla Atribacteria, Hydrogenedentes and Marinimicrobia in methanogenic environments. Metabolic reconstruct

SUBMITTER: Nobu MK 

PROVIDER: S-EPMC4511927 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature