A step toward simplified detection of serum albumin on SDS-PAGE using an environment-sensitive flavone sensor.

ABSTRACT: In this study, we report a series of novel flavone-based sensors that exhibit a superior fluorescence response when interacting with serum albumin in real serum samples and in acrylamide gels. The detection limit of probe 4 for serum albumin solution is 0.09 μg mL(-1), and the detectable volume for monkey serum reaches as low as 0.03 μL.

SUBMITTER: Liu B 

PROVIDER: S-EPMC4512168 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature