Negative symptoms in youths with psychosis spectrum features: complementary scales in relation to neurocognitive performance and function.

ABSTRACT:

Background

Negative symptoms in schizophrenia are related to impaired functioning. The presence of negative symptoms in early phases of psychosis in individuals at clinical risk is receiving increased attention.

Methods

We evaluated comprehensively a sample of 92 young people (age range 15-25) applying the Clinical Assessment Interview for Negative Symptoms (CAINS), adapted for youth. Individuals at clinical high risk (CHR, n=29) were compared to individuals with schizophrenia (SZ, n=31) and normal controls (NC, n=32). In addition to the CAINS, participants were assessed with the Structured Interview for Prodromal Syndromes (SIPS), enabling examination of the relations among scales, as well as the Penn Computerized Neurocognitive Battery (CNB), to examine association with co

SUBMITTER: Gur RE 

PROVIDER: S-EPMC4512843 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature