Muscle Strength and Changes in Physical Function in Women With Systemic Lupus Erythematosus.

ABSTRACT:

Objective

Cross-sectional studies have observed that muscle weakness is associated with worse physical function among women with systemic lupus erythematosus (SLE). The present study examines whether reduced upper and lower extremity muscle strength predict declines in function over time among adult women with SLE.

Methods

One hundred forty-six women from a longitudinal SLE cohort participated in the study. All measures were collected during in-person research visits approximately 2 years apart. Upper extremity muscle strength was assessed by grip strength. Lower extremity muscle strength was assessed by peak knee torque of extension and flexion. Physical function was assessed using the Short Physical Performance Battery (SPPB). Regression analyses modeled associations of ba

SUBMITTER: Andrews JS 

PROVIDER: S-EPMC4515406 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature