Clinical and imaging assessment of acute combat mild traumatic brain injury in Afghanistan.

ABSTRACT:

Objective

To evaluate whether diffusion tensor imaging (DTI) will noninvasively reveal white matter changes not present on conventional MRI in acute blast-related mild traumatic brain injury (mTBI) and to determine correlations with clinical measures and recovery.

Methods

Prospective observational study of 95 US military service members with mTBI enrolled within 7 days from injury in Afghanistan and 101 healthy controls. Assessments included Rivermead Post-Concussion Symptoms Questionnaire (RPCSQ), Post-Traumatic Stress Disorder Checklist Military (PCLM), Beck Depression Inventory (BDI), Balance Error Scoring System (BESS), Automated Neuropsychological Assessment Metrics (ANAM), conventional MRI, and DTI.

Results

Significantly greater impairment was observed in partic

SUBMITTER: Adam O 

PROVIDER: S-EPMC4516289 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature