Associations Between Ankle-Brachial Index and Cognitive Function: Results From the Lifestyle Interventions and Independence for Elders Trial.

ABSTRACT:

Objective

The objective of this study was to evaluate cross-sectional and longitudinal associations between ankle-brachial index (ABI) and indicators of cognitive function.

Design

Randomized clinical trial (Lifestyle Interventions and Independence for Elders Trial).

Setting

Eight US academic centers.

Participants

A total of 1601 adults ages 70-89 years, sedentary, without dementia, and with functional limitations.

Measurements

Baseline ABI and interviewer- and computer-administered cognitive function assessments were obtained. These assessments were used to compare a physical activity intervention with a health education control. Cognitive function was reassessed 24 months later (interviewer-administered) and 18 or 30 months later (computer-administered)

SUBMITTER: Espeland MA 

PROVIDER: S-EPMC4516564 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature