Association of Adiponectin With Body Composition and Mortality in Hemodialysis Patients.

ABSTRACT:

Background

In the general population, circulating adiponectin is associated with a favorable cardiovascular risk profile (eg, lower triglycerides and body fat) and decreased mortality. Hemodialysis (HD) patients have comparatively higher adiponectin concentrations, but prior studies examining the adiponectin-mortality association in this population have not accounted for body composition or shown a consistent relationship.

Study design

Prospective cohort study.

Settings & participants

We examined baseline serum adiponectin concentrations in 501 HD patients across 13 dialysis centers from the prospective MADRAD (Malnutrition, Diet, and Racial Disparities in Chronic Kidney Disease) cohort (entry period, October 2011 to February 2013; follow-up through August 2013).

P

SUBMITTER: Rhee CM 

PROVIDER: S-EPMC4516594 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature