High-Resolution Imaging of the Optic Nerve and Retina in Optic Nerve Hypoplasia.

ABSTRACT:

Purpose

To investigate the optic nerve and macular morphology in patients with optic nerve hypoplasia (ONH) using spectral-domain optical coherence tomography (SD OCT).

Design

Prospective, cross-sectional, observational study.

Subjects

A total of 16 participants with ONH (10 female and 6 male; mean age, 17.2 years; 6 bilateral involvement) and 32 gender-, age-, ethnicity-, and refraction-matched healthy controls.

Methods

High-resolution SD OCT (Copernicus [Optopol Technology S.A., Zawiercie, Poland], 3 μm resolution) and handheld SD OCT (Bioptigen Inc [Research Triangle Park, NC], 2.6 μm resolution) devices were used to acquire horizontal scans through the center of the optic disc and macula.

Main outcome measures

Horizontal optic disc/cup and rim diamet

SUBMITTER: Pilat A 

PROVIDER: S-EPMC4518044 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature