Urinary adiponectin and albuminuria in non-diabetic hypertensive patients: an analysis of the ESPECIAL trial.

ABSTRACT:

Background

Although adiponectin levels have been reported to be correlated with albuminuria, this issue remains unresolved in non-diabetic hypertensive subjects, particularly when urinary adiponectin is considered.

Methods

Urinary adiponectin levels were examined using an enzyme-linked immunosorbent assay in 229 participants. who used olmesartan as a hypertensive agent. Their albuminuria levels were measured for 16 weeks after randomization and initiation of conventional or intensive diet education. Linear or logistic regression models were applied, as appropriate, to explore the relationship with albuminuria itself or its response after the intervention.

Results

Urinary adiponectin levels were positively related to baseline albuminuria level (r = 0.529). After adjust

SUBMITTER: Han SS 

PROVIDER: S-EPMC4522110 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature