EPHX1 rs2234922 polymorphism and lung cancer susceptibility in Asian populations: a meta-analysis.

ABSTRACT:

Objective

Polymorphisms of epoxide hydrolase 1 (EPHX1) rs2234922 have been reported to be associated with variations in EPHX1 activity. Many studies have investigated the association between EPHX1 rs2234922 polymorphism and lung cancer risk, but their results have been inconsistent. The purpose of this study was to perform a meta-analysis of all eligible studies to derive a more precise estimation of the associations of EPHX1 rs2234922 polymorphism with lung cancer.

Methods

The PubMed was searched for case-control studies published up to Oct 01, 2014. Data were extracted and pooled odds ratios (ORs) with 95% confidence interval (CI) were calculated. The pooled ORs for the risk associated with the genotypes of homozygote G/G and G allele carriers (A/G + G/G) with the A/A geno

SUBMITTER: Xu X 

PROVIDER: S-EPMC4522474 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature