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Glutathione-coordinated [2Fe-2S] cluster: a viable physiological substrate for mitochondrial ABCB7 transport.


ABSTRACT: The glutathione-coordinated [2Fe-2S] cluster is demonstrated to be a viable and likely substrate for physiological iron-sulfur cluster transport by Atm1p, a mitochondrial ABC export protein. Flow cytometry and colorimetric assays demonstrate a quantitative methodology for study of metal translocation proteins and their proteoliposome products.

SUBMITTER: Li J 

PROVIDER: S-EPMC4522903 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature