What Are the Prognostic Factors for Radiographic Progression of Knee Osteoarthritis? A Meta-analysis.

ABSTRACT:

Background

A previous systematic review on prognostic factors for knee osteoarthritis (OA) progression showed associations for generalized OA and hyaluronic acid levels. Knee pain, radiographic severity, sex, quadriceps strength, knee injury, and regular sport activities were not associated. It has been a decade since the literature search of that review and many studies have been performed since then investigating prognostic factors for radiographic knee OA progression.

Questions/purposes

The purpose of this study is to provide an updated systematic review of available evidence regarding prognostic factors for radiographic knee OA progression.

Methods

We searched for observational studies in MEDLINE and EMBASE. Key words were: knee, osteoarthritis (or arthritis, or a

SUBMITTER: Bastick AN 

PROVIDER: S-EPMC4523522 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature