Variants in multiple genes polymorphism association analysis of COPD in the Chinese Li population.

ABSTRACT:

Background

It is known that the contribution of risk alleles to chronic obstructive pulmonary disease (COPD) may vary between populations. Further, previous studies involving various ethnic groups have revealed associations between COPD and genetic polymorphisms in families with sequence similarity 13, member A (FAM13A), micro-RNA 2054 (MIR2054), SET domain containing protein 7 (SETD7), ring finger protein 150 (RNF150), hedgehog interacting protein (HHIP), and vascular endothelial growth factor A (VEGFA). Our objective was to explore the association between these gene polymorphism and COPD in members of Chinese Li minority population.

Materials and methods

The Chinese Li population case-control study was conducted to assess genetic associations with COPD risk. Seven single n

SUBMITTER: Ding Y 

PROVIDER: S-EPMC4524388 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature