PSTR Finder: a rapid method to discover polymorphic short tandem repeat markers from whole-genome sequences.

ABSTRACT:

Background

Whole-genome sequencing is performed routinely as a means to identify polymorphic genetic loci such as short tandem repeat loci. We have developed a simple tool, called pSTR Finder, which is freely available as a means of identifying putative polymorphic short tandem repeat (STR) loci from data generated from genome-wide sequences. The program performs cross comparisons on the STR sequences generated using the Tandem Repeats Finder based on multiple-genome samples in a FASTA format. These comparisons generate reports listing identical, polymorphic, and different STR loci when comparing two samples.

Methods

The web site http://forensic.mc.ntu.edu.tw:9000/PSTRWeb/Default has been developed as a means to identify polymorphic STR loci within complex mass genome sequen

SUBMITTER: Lee JC 

PROVIDER: S-EPMC4525727 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature