Retinal topography maps in R: new tools for the analysis and visualization of spatial retinal data.

ABSTRACT: Retinal topography maps are a widely used tool in vision science, neuroscience, and visual ecology, providing an informative visualization of the spatial distribution of cell densities across the retinal hemisphere. Here, we introduce Retina, an R package for computational mapping, inspection of topographic model fits, and generation of average maps. Functions in Retina take cell count data obtained from retinal wholemounts using stereology software. Accurate visualizations and comparisons between different eyes have been difficult in the past, because of deformation and incisions of retinal wholemounts. We account for these issues by incorporation of the R package Retistruct, which results in a retrodeformation of the wholemount into a hemispherical shape, similar to the original eyecup.

SUBMITTER: Cohn BA 

PROVIDER: S-EPMC4527213 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature