HbA1c as screening for gestational diabetes mellitus in women with polycystic ovary syndrome.

ABSTRACT:

Background

Gestational diabetes mellitus (GDM) is associated with adverse pregnancy outcomes such as preeclampsia and macrosomia. Women with polycystic ovary syndrome (PCOS) are at increased risk of developing GDM. Today, GDM is diagnosed by oral glucose tolerance test (OGTT), a rather cumbersome test for the women and health care system. The objectives of this study were to investigate whether HbA1c in first trimester of pregnancy could be used as a screening test for GDM in first trimester and throughout pregnancy in order to reduce the number of OGTTs, and whether it could predict preeclampsia and macrosomia in women with PCOS.

Methods

Post hoc analyses of data from 228 women from a prospective, randomised, multicenter study comparing metformin to placebo from first trime

SUBMITTER: Odsæter IH 

PROVIDER: S-EPMC4527320 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature