Emergency department-initiated buprenorphine/naloxone treatment for opioid dependence: a randomized clinical trial.

ABSTRACT:

Importance

Opioid-dependent patients often use the emergency department (ED) for medical care.

Objective

To test the efficacy of 3 interventions for opioid dependence: (1) screening and referral to treatment (referral); (2) screening, brief intervention, and facilitated referral to community-based treatment services (brief intervention); and (3) screening, brief intervention, ED-initiated treatment with buprenorphine/naloxone, and referral to primary care for 10-week follow-up (buprenorphine).

Design, setting, and participants

A randomized clinical trial involving 329 opioid-dependent patients who were treated at an urban teaching hospital ED from April 7, 2009, through June 25, 2013.

Interventions

After screening, 104 patients were randomized to the referral g

SUBMITTER: D'Onofrio G 

PROVIDER: S-EPMC4527523 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature