A Systems Approach to Elucidate Heterosis of Protein Abundances in Yeast.

ABSTRACT: Heterosis is a universal phenomenon that has major implications in evolution and is of tremendous agro-economic value. To study the molecular manifestations of heterosis and to find factors that maximize its strength, we implemented a large-scale proteomic experiment in yeast. We analyzed the inheritance of 1,396 proteins in 55 inter- and intraspecific hybrids obtained from Saccharomyces cerevisiae and S. uvarum that were grown in grape juice at two temperatures. We showed that the proportion of heterotic proteins was highly variable depending on the parental strain and on the temperature considered. For intraspecific hybrids, this proportion was higher at nonoptimal temperature. Unexpectedly, heterosis for protein abundance was strongly biased toward positive values in interspecific hybri

SUBMITTER: Blein-Nicolas M 

PROVIDER: S-EPMC4528237 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature