Interactions between multiple helminths and the gut microbiota in wild rodents.

ABSTRACT: The gut microbiota is vital to host health and, as such, it is important to elucidate the mechanisms altering its composition and diversity. Intestinal helminths are host immunomodulators and have evolved both temporally and spatially in close association with the gut microbiota, resulting in potential mechanistic interplay. Host-helminth and host-microbiota interactions are comparatively well-examined, unlike microbiota-helminth relationships, which typically focus on experimental infection with a single helminth species in laboratory animals. Here, in addition to a review of the literature on helminth-microbiota interactions, we examined empirically the association between microbiota diversity and composition and natural infection of multiple helminth species in wild mice (Apodemus flavi

SUBMITTER: Kreisinger J 

PROVIDER: S-EPMC4528493 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature