Impulsive traits and unplanned suicide attempts predict exaggerated prefrontal response to angry faces in the elderly.

ABSTRACT:

Objective

Abnormal responses to social stimuli are seen in people vulnerable to suicidal behavior, indicating possible disruptions in the neural circuitry mediating the interpretation of socioemotional cues. These disruptions have not been empirically related to psychological and cognitive pathways to suicide. In the present study of older suicide attempters, we examined neural responses to emotional faces and their relationship to impulsivity, one of the components of the suicidal diathesis.

Methods

Using functional magnetic resonance imaging, we recorded neurohemodynamic responses to angry faces in a carefully characterized sample of 18 depressed elderly with history of suicide attempts, 13 depressed nonsuicidal patients, and 18 healthy individuals, all aged 60+. Impulsivi

SUBMITTER: Vanyukov PM 

PROVIDER: S-EPMC4528975 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature