Erythropoietin and Neonatal Neuroprotection.

ABSTRACT: Certain groups of neonates are at high risk of developing long-term neurodevelopmental impairment and might be considered candidates for neuroprotective interventions. This article explores some of these high-risk groups, relevant mechanisms of brain injury, and specific mechanisms of cellular injury and death. The potential of erythropoietin (Epo) to act as a neuroprotective agent for neonatal brain injury is discussed. Clinical trials of Epo neuroprotection in preterm and term infants are updated.

SUBMITTER: Juul SE 

PROVIDER: S-EPMC4529536 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature