MetazSecKB: the human and animal secretome and subcellular proteome knowledgebase.

ABSTRACT: The subcellular location of a protein is a key factor in determining the molecular function of the protein in an organism. MetazSecKB is a secretome and subcellular proteome knowledgebase specifically designed for metazoan, i.e. human and animals. The protein sequence data, consisting of over 4 million entries with 121 species having a complete proteome, were retrieved from UniProtKB. Protein subcellular locations including secreted and 15 other subcellular locations were assigned based on either curated experimental evidence or prediction using seven computational tools. The protein or subcellular proteome data can be searched and downloaded using several different types of identifiers, gene name or keyword(s), and species. BLAST search and community annotation of subcellular locations ar

SUBMITTER: Meinken J 

PROVIDER: S-EPMC4529745 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature