Insulin resistance, metabolic syndrome, and lung function in US adolescents with and without asthma.

ABSTRACT:

Background

Obesity increases both the risk of asthma and asthma severity and is a well-known risk factor for insulin resistance and the metabolic syndrome (MS) in children and adolescents.

Objective

We aimed to examine the association among obesity, insulin sensitivity, MS, and lung function in US adolescents with and without asthma.

Methods

We performed a cross-sectional study of 1429 adolescents aged 12 to 17 years in the 2007-2010 National Health and Nutrition Examination Survey. Adjusted regression was used to assess the relationships among obesity, insulin sensitivity/resistance, MS, and lung function in children with and without asthma.

Results

Insulin resistance was negatively associated with FEV1 and forced vital capacity (FVC) in adolescents with and w

SUBMITTER: Forno E 

PROVIDER: S-EPMC4530022 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature